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    Thus, the presence of the multiply resistant ST 59/PFT USA 1000 CAMRSA clone containing the PVL genes circulating in the community has the capability of sharply limiting therapeutic options should it become widespread.

    ACKNOWLEDGMENTS

    This study was supported by grants from the CDC (R01 CCR523379), the National Institutes of Health (R01 AI40481-01A1), the TSGH (TSGH-C92-77), and The Grant Healthcare Foundation (Lake Forest, IL).

    We are grateful to Linda McDougal from the CDC (Atlanta, GA) for comparing the pulsed-field types of the isolates described herein with those in the national database. We are grateful to Daniel Kim for providing assistance with and maintaining the MRSA database.

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